Recurrent Glioblastoma Multiforme Treatment is typically tailored to each patient and can involve a combination of surgical

 

Recurrent Glioblastoma Multiforme Treatment

Recurrent Glioblastoma Multiforme (rGBM) is a type of brain cancer that is characterized by its aggressive behavior and high resistance to conventional treatments. It has a poor prognosis and is one of the most challenging cancers to treat. Despite advances in cancer treatment, the survival rate for patients with rGBM remains low, with a median survival time of just over 12 months.

Recurrent Glioblastoma Multiforme Treatment is typically tailored to each patient and can involve a combination of surgical, radiation, and chemotherapy approaches. The goal of treatment is to slow the progression of the cancer, relieve symptoms, and extend survival time.

Surgery is often the first line of Recurrent Glioblastoma Multiforme Treatment. The aim of surgery is to remove as much of the cancerous tissue as possible while preserving healthy brain function. This may involve the removal of the entire tumor or just a portion of it, depending on its location and size.

Radiation therapy is another common Recurrent Glioblastoma Multiforme Treatment. It is typically used after surgery and can help to destroy any remaining cancer cells, shrink the size of the tumor, and relieve symptoms. The most commonly used type of radiation therapy for rGBM is external beam radiation therapy (EBRT). This involves delivering high-energy beams of radiation directly to the cancerous tissue.

Chemotherapy is also a common treatment for rGBM. It involves the use of drugs to destroy cancer cells. Chemotherapy can be administered in a variety of ways, including intravenously, orally, or directly into the spinal fluid. The most commonly used chemotherapy drugs for rGBM include temozolomide and carboplatin.

Another approach to treating rGBM is immunotherapy. This type of therapy aims to stimulate the body's immune system to attack the cancer cells. There are a number of different immunotherapy drugs available for rGBM, including immune checkpoint inhibitors, CAR-T cell therapy, and vaccines.

In recent years, there has also been increasing interest in the use of targeted therapy for rGBM. Targeted therapy is a type of treatment that focuses on specific genes, proteins, or molecular pathways involved in the growth and spread of cancer cells. Some of the targeted therapy drugs used for rGBM include bevacizumab, lomustine, and sunitinib.

In addition to these standard treatments, there are a number of clinical trials underway to evaluate new treatments for rGBM. These trials are testing a range of new drugs and approaches, including new chemotherapy drugs, immunotherapy drugs, and gene therapies.

Finally, it is important for patients with rGBM to receive supportive care during their treatment. This may include physical therapy, rehabilitation, and other therapies to help manage symptoms and improve quality of life.