Modern Healthcare Relies Heavily on the Microbiome Because of its Multiple Functions

 

Human Microbiome
Human Microbiome 

Despite having nearly identical genetics, there is a huge diversity of phenotypes among humans due to the minute variations in our DNA. In contrast, the human microbiome's metagenome—the total amount of DNA found in the microbes that live inside our bodies is much more variable, with the majority of healthy people only sharing a third of its constituent genes. Thus, since at least the 1960s through the Human Microbiome Project and beyond, comprehending this variability in the "healthy microbiome" has been a significant challenge in microbiome research.

The Global Human Microbiome Market is estimated to be valued at US$ 91,075.4 Mn in 2021 and is expected to exhibit a CAGR of 18.9% over the forecast period (2021-2028).

A single microbe, such as a bacteria, fungus, or virus, was identified, isolated, and cultured in the past for the purpose of studying human microbiome. These pathogen-fighting therapies and medications were developed by scientists using the organisms they collected from patients with acute or chronic infections. Although treating human illness with this strategy has been incredibly effective, it's important to remember that this strategy has also produced bacteria that are resistant to antibiotics. Recent investigations into the human microbiota offer great hope for a novel strategy to improve human health and wellbeing.

The ranges and diversity of both taxonomic compositions and functional potentials typically observed in the microbiomes of healthy populations, as well as potential driving factors like geography, diet, and lifestyle, have been documented in a number of population-scale studies toward this goal. In this article, we examine various definitions of a "healthy microbiome," the ranges of a healthy microbial diversity, and unresolved issues that need to be addressed in the future, such as the characterization of molecular function and the development of ecological therapies.

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