Polio vaccines are vaccines used to prevent poliomyelitis

 

Polio Vaccines Market
Polio vaccines 

Human enteroviruses of the Picornaviridae family are thought to be the primary cause of the acutely contagious disease known as poliomyelitis. Due to poor sanitation and personal hygiene, polioviruses may spread by faecal to oral or oral to oral transmission routes. Children can be immunised against polio with vaccinations such as the oral polio vaccine (OPV) and the inactivated poliomyelitis vaccine (IPV). The IPV contains three poliovirus strains, Mahoney type 1, MEF-1 (Middle East Forces) type 2, and Saukett type 3, while the OPV contains live attenuated versions of similar viruses. Oral administration is used for OPV whereas injectable administration is used for IPV.

Poliomyelitis is a highly contagious illness brought on by the poliovirus. Infantile paralysis and polio are other names for it. The virus is a single-stranded RNA virus that belongs to the genus Enterovirus. The poliovirus has three serotypes: P1, P2, and P3. Developing antibody to one serotype does not result in a significant amount of immunity to the other serotypes. The virus is mainly spread through the fecal-oral channel, through drinking contaminated water or food, and less frequently through the oral-oral route. Even in the absence of symptoms, those who are sick can spread the illness for up to 6 weeks. After roughly a week, the poliovirus invades local lymphoid tissue, enters the circulation, and may then infect cells in the central nervous system. The poliovirus initially colonises the gastrointestinal tract, more especially the intestine and oropharynx. The usual poliomyelitis symptoms are caused by the poliovirus replicating in motor neurons of the anterior horn and brain stem, which leads to cell death. Over the course of the projection period, this is expected to encourage a large increase in the polio vaccines.

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