Dengue Vaccine : Dengue Fever, Causes, Complications

 

Dengue vaccine is a human vaccine that prevents dengue disease. The necessity to produce immunisation against all four dengue serotypes hampered the development of dengue vaccines, which began in the 1920s. Only dengue seropositive persons aged 9–45 years in dengue endemic areas are eligible to get this vaccination. It's given subcutaneously in a three-dose sequence spaced six months apart (0, 6, 12 months).

Dengue vaccine will be more complicated than measles or mumps vaccines: Dengue fever is caused by four viruses that are related but not the same. They vary in antigenicity, implying that any vaccine you produce must protect against not one, but four viruses. DENV-1, DENV-2, DENV-3, and DENV-4 are the four dengue virus serotypes. They are members of the Flavivirus genus and family Flaviviridae (of which the yellow fever virus is the type species), which includes about 53 viruses. Dengue fever can hit you repeatedly. Dengue fever can be contracted not once, twice, or even three times, with each succeeding infection being more deadly than the previous. The presence of viral antigens and DENV RNA in brain tissue and cerebrospinal fluid (CSF) samples has indicated Dengue virus infection of the CNS. Infiltrates of infected macrophages appear to be the route by which the virus enters the brain. Dengue Vaccine can be very beneficial.


Dengue Vaccines Market


Your white blood cell and platelet counts may drop as a result of dengue fever. The typical platelet count in the body is 1.5 to 4 lacs, but in dengue patients, this can drop to as low as 20,000 to 40,000. There is no human-to-human transmission of dengue disease. Once a mosquito is infected, it is infected for the rest of its life. It only takes one mosquito bite to spread the dengue virus and make you sick for days. Dengue fever can cause shock, internal haemorrhage, and even death in severe cases.

The Aedes Aegypti mosquito, also known as the dengue mosquito, is dark in colour with typical white leg patterns and lyre-like markings on the thorax. It is much tiny, measuring about 4 to 7 centimetres in length. When a dengue mosquito bites you, the virus is transmitted and dengue fever symptoms might occur. The individual bitten by the mosquito may experience very minor symptoms, in which case treatment is not difficult. However, if a person develops severe dengue symptoms, medical help is required immediately.

 

 

 

 

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